CAS 110-05-4 refers to 2,2'-Azobisisobutyronitrile (AIBN), a well - known organic compound that finds extensive use in various industrial and laboratory applications. As a supplier of CAS 110 - 05 - 4, it is crucial to understand not only its uses but also the associated health hazards.
Physical and Chemical Properties of CAS 110 - 05 - 4
AIBN is a white to off - white crystalline powder. It is insoluble in water but soluble in organic solvents such as benzene, toluene, and acetone. One of its most notable properties is its ability to decompose upon heating or exposure to certain initiators, releasing nitrogen gas and generating free radicals. This property makes it a popular initiator in polymerization reactions, where it helps to start the chain - growth process of monomers.
Health Hazards
Inhalation
Inhalation of AIBN dust or vapors can pose significant health risks. When inhaled, the compound can irritate the respiratory tract. Symptoms may include coughing, shortness of breath, and throat irritation. Prolonged or high - level inhalation exposure can lead to more severe respiratory problems, such as bronchitis or even pulmonary edema. The free radicals generated by AIBN decomposition can react with the cells lining the respiratory tract, causing oxidative stress and damage to the delicate tissues.
Skin Contact
Skin contact with AIBN can cause irritation, redness, and itching. The compound can penetrate the skin and potentially cause allergic reactions in some individuals. Repeated or prolonged skin exposure may lead to more severe dermatitis, characterized by blistering, scaling, and in some cases, secondary infections. Workers handling AIBN in industrial settings are at a particular risk, especially if proper personal protective equipment (PPE) such as gloves and protective clothing is not worn.
Eye Contact
AIBN is highly irritating to the eyes. Contact with the eyes can cause immediate pain, redness, and tearing. If not promptly and thoroughly rinsed, it can lead to more serious eye damage, including corneal abrasions and even permanent vision impairment. In laboratory or industrial environments, safety goggles should always be worn to prevent accidental eye exposure.
Ingestion
Ingesting AIBN is extremely dangerous. It can cause nausea, vomiting, abdominal pain, and diarrhea. In severe cases, it can lead to systemic toxicity, affecting the liver, kidneys, and other vital organs. The free radicals generated by AIBN in the body can cause oxidative damage to cells and tissues, disrupting normal physiological functions.
Safety Measures
As a supplier of CAS 110 - 05 - 4, we are committed to providing information on safety measures to minimize the health risks associated with this compound.
Personal Protective Equipment (PPE)
Workers handling AIBN should wear appropriate PPE, including gloves made of materials resistant to chemical penetration, safety goggles, and protective clothing. Respirators may also be necessary in environments where there is a risk of inhalation exposure, especially in areas with poor ventilation.
Ventilation
Proper ventilation is essential when working with AIBN. Adequate local exhaust ventilation should be installed in areas where the compound is used or stored to remove dust and vapors from the air. General ventilation can also help to maintain a safe working environment by diluting any potentially hazardous concentrations.
Storage
AIBN should be stored in a cool, dry place away from heat sources, oxidizing agents, and incompatible materials. It should be kept in tightly sealed containers to prevent leakage and dust formation. Storage areas should be well - marked and restricted to authorized personnel only.
Handling and Disposal
When handling AIBN, it is important to follow strict operating procedures. Avoid generating dust by using appropriate handling techniques, such as pouring and transferring in a controlled manner. Spills should be cleaned up immediately using proper absorbent materials, and the waste should be disposed of in accordance with local environmental regulations.
Comparison with Other Organic Peroxides
There are other organic peroxides in the market with different CAS numbers, each having its own set of properties and health hazards. For example, TBEC | CAS 34443 - 12 - 4 | Tert - butyl (2 - ethylhexyl) Monoperoxy Carbonate is also used as an initiator in polymerization reactions. Like AIBN, it can be hazardous if not handled properly. It is a flammable liquid and can cause skin and eye irritation.
TBPIN | CAS 13122 - 18 - 4 | Tert - butylperoxy - 3,5,5 - trimethylhexanoate is another organic peroxide. It is sensitive to heat, shock, and friction and can decompose violently, posing a significant explosion risk. In addition to the physical hazards, it can also cause health problems similar to AIBN, such as skin and respiratory irritation.
DTAP | CAS 10508 - 09 - 5 | Di - tert - amyl Peroxide is a highly reactive organic peroxide. It is a strong oxidizing agent and can react vigorously with reducing agents, combustible materials, and other incompatible substances. Health hazards associated with DTAP include severe skin and eye burns and inhalation toxicity.
Conclusion
As a supplier of CAS 110 - 05 - 4, we understand the importance of providing our customers with comprehensive information about the health hazards associated with this compound. While AIBN is a valuable chemical in many industrial and laboratory processes, it must be handled with extreme caution to prevent health risks. By following proper safety measures, including the use of PPE, adequate ventilation, and correct storage and handling procedures, the risks can be minimized.
If you are interested in purchasing CAS 110 - 05 - 4 or have any questions regarding its safe use, we encourage you to contact us for further discussion and negotiation. We are committed to providing high - quality products and ensuring the safety of our customers.
References
- Bretherick, L. (2007). Bretherick's Handbook of Reactive Chemical Hazards. Elsevier.
- Sax, N. I., & Lewis, R. J. (1989). Sax's Dangerous Properties of Industrial Materials. Van Nostrand Reinhold.
- The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals. (2006). Merck & Co.