Butyryl Chloride, also known as Butanoyl Chloride, is an aliphatic acyl chloride used to introduce a butyryl group into organic synthesis. It has the molecular formula C₄H₇ClO, molecular weight 106.55 g/mol, and CAS No. 141-75-3. The acid chloride group provides a direct route for acylation where a four-carbon aliphatic acyl structure is required.
Key Specifications
|
Parameter |
Value |
|
Chemical Name |
Butyryl Chloride |
|
Synonym |
Butanoyl Chloride |
|
CAS No. |
141-75-3 |
|
Molecular Formula |
C₄H₇ClO |
|
Molecular Weight |
106.55 g/mol |
|
Appearance |
Clear, colorless liquid |
|
Density at 20°C |
Approx. 1.026 g/cm³ |
|
Boiling Point |
Approx. 101–102°C |
|
Melting Point |
Approx. −89°C |
|
Flash Point |
Approx. 18°C |
Product Characteristics
Four-Carbon Acyl Structure
The molecule contains a linear four-carbon acyl group, making it suitable for synthesis routes requiring a defined butyryl structure.
Reactive Acid Chloride Group
The acid chloride functionality provides a direct reaction site for acylation and downstream functionalization.
Defined Physical Profile
Its molecular weight, density, boiling point, and melting point provide practical reference data for material identification and process planning.
Application Fit
Organic Synthesis
Used as an acylating reagent when a butyryl group is required in the target molecule.
Intermediate Synthesis
Applicable to reaction sequences in which the butanoyl structure becomes part of a downstream chemical intermediate.
Specialty Chemical Processes
Suitable for synthesis routes requiring a defined aliphatic acyl chloride as a controlled chemical input.
Process Selection
Target Molecular Structure
Butyryl Chloride is appropriate when the required product structure contains a butyryl-derived acyl group.
Reaction Compatibility
The acid chloride functionality suits acylation routes where direct introduction of the acyl group is part of the reaction sequence.
Scale-Up Review
Before process scale-up, confirm assay, moisture specification, impurity limits, addition conditions, and material compatibility against the process requirements.
Quality Control Points
Identity
CAS No., molecular formula, molecular weight, appearance, and other agreed identification parameters should match the approved specification.
Assay and Impurities
Assay and specified impurity limits should be controlled according to the requirements of the downstream process.
Physical Properties
Density and boiling range can support incoming-material verification and routine batch assessment.
Handling and Storage
Moisture Control
Butyryl Chloride is moisture-sensitive. Containers should remain tightly closed during storage and handling.
Temperature Management
Storage conditions should follow the applicable SDS, product specification, and transportation requirements.
Container Condition
Check sealing condition, labeling, batch identification, and container integrity before material release for use.
Documentation for Procurement
Technical Data
The TDS should provide the chemical identity, agreed specifications, physical properties, and relevant quality parameters.
Safety Data
The current SDS should be reviewed for handling, storage, transport, and regulatory information.
Batch Certificate
The COA should identify the batch and report test results against the agreed specification.
Packaging and Supply
Packaging Selection
Packaging should be compatible with the chemical properties and selected according to quantity, transport conditions, and applicable requirements.
Batch Traceability
Batch numbers should correspond with the product label and quality documentation throughout the supply process.
Shipment Documents
Product labeling, transport classification, shipping documents, and required technical files should be confirmed before dispatch.
FAQ
Q: What is Butyryl Chloride used for?
A: Butyryl Chloride is used as an acylating reagent for introducing a butyryl group into organic synthesis and intermediate production.
Q: What is the CAS number of Butyryl Chloride?
A: The CAS No. is 141-75-3.
Q: What is the molecular weight of Butyryl Chloride?
A: The molecular weight is 106.55 g/mol.
Q: Is Butyryl Chloride an aliphatic acyl chloride?
A: Yes. It is an aliphatic acyl chloride containing a linear four-carbon acyl structure.
Q: What documents are useful for material evaluation?
A: The main documents are the current TDS, SDS, and batch COA, together with the agreed product specification.
Q: What information should be included in an enquiry?
A: Include the required quantity, target specification, packaging requirement, destination, and required technical or regulatory documents.
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