Pivaloyl Chloride

Pivaloyl Chloride is an aliphatic acyl chloride used to introduce a pivaloyl group into organic synthesis. It is also known as 2,2-Dimethylpropanoyl Chloride and Trimethylacetyl Chloride.

The product has CAS No. 3282-30-2, molecular formula C₅H₉ClO, and molecular weight 120.58 g/mol. Its branched molecular structure is relevant to synthesis routes requiring a defined 2,2-dimethylpropanoyl group.

Branched Acyl Group
The molecule contains a 2,2-dimethylpropanoyl group, giving the product a defined branched aliphatic structure for synthesis.

Acid Chloride Reactivity
The acid chloride functional group provides a direct route for introducing the pivaloyl group into suitable organic substrates.

Low-Temperature Physical Profile
The low melting point allows the material to remain liquid across a broad working temperature range under appropriate handling conditions.

Organic Synthesis
Used in acylation reactions where a pivaloyl group is required in the target molecule or intermediate.

Specialty Intermediates
Suitable for synthesis routes involving intermediates that require a branched aliphatic acyl structure.

Chemical Derivatization
The reactive acid chloride group can be used to prepare pivaloyl-containing derivatives under controlled reaction conditions.

Chemical Identity
CAS No., molecular formula, molecular weight, and structural requirement should match the intended synthesis route.

Assay Requirement
The required assay should be defined according to reaction stoichiometry, downstream specifications, and the applicable analytical method.

Physical Properties
Density, melting point, and boiling point provide useful reference data for material identification and process planning.

Identity
Identity testing confirms the chemical structure against the specified product and CAS No.

Assay
Assay testing establishes the concentration of the target compound for reaction calculations and specification control.

Physical Checks
Appearance and defined physical properties can be included in batch inspection according to the agreed product specification.

Closed Packaging
Pivaloyl Chloride should be kept in tightly sealed packaging suitable for reactive acid chloride materials.

Moisture Control
Contact with moisture should be minimized during storage and handling because acid chlorides react with water.

Temperature Control
Storage temperature should follow the applicable product specification and safety documentation, with packaging integrity maintained throughout storage.

Product Specification
The specification should state chemical identity, assay, physical parameters, and applicable acceptance criteria.

Batch Records
Batch-specific analytical records provide traceability for incoming inspection and production use.

Safety Documents
Current safety and transport documentation should be available for handling, storage, and shipment planning.

Acylation
The product is applicable to synthesis steps requiring introduction of a pivaloyl group through acid chloride chemistry.

Molar Calculation
The molecular weight of 120.58 g/mol provides the basis for calculating reagent quantities and reaction stoichiometry.

Volume Calculation
The density of approximately 0.980 g/mL at 20 °C can be used when converting between measured volume and material mass.

Grade
The required grade should correspond to the reaction requirements, assay target, and analytical acceptance criteria.

Quantity
Required quantity can be defined according to laboratory evaluation, process development, pilot production, or routine manufacturing.

Packaging Format
Packaging selection should reflect quantity, transport conditions, storage duration, and site handling requirements.

Why This Product Fits Aliphatic Acyl Chloride Requirements
Pivaloyl Chloride combines an acid chloride group with a branched 2,2-dimethylpropanoyl structure. The specific structure is relevant when a synthesis route requires the pivaloyl group rather than a linear aliphatic acyl group.

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